put new chorus 11 on a spc project black tarmac sl3 last summer, raced it hard with my 404 tubies (bike is not uci legal! o yeh!) and it is dead on. just built up a spc allez comp (alu, is same geometry as race rig) with new athena 11 (2012 athena black finish, dual pivots front and rear) as the winter trainer/commuter and that rig is smooth as silk.
at the shop, we check even the new bike builds for der. hanger alignment, in reference to an earlier post regarding shifting issues.
also, wheel brands have specific spacer requirements behind the freehub body when moving from 8/9/10 to 11 speed, e.g. zipp requires two 0.25 mm spacers where the older speeds use only one.
another consideration on new gruppo or drivetrain builds is to go and ride the thing, put 20, 40 miles on it to let the new chain mate to the cogs in the rear and allow everything to settle a bit.
i continue to sell off my 10 speed stuff on ebay, mostly cassettes, but am lovin the 11......